Treatment of the mesotelioma

Treatment of the mesotelioma
The treatment of the mesotelioma continues three standardized and recognized procedures: operation, chemotherapy, and radiation. There are many ways of tackling these three treatments for the mesotelioma. There are doctors who prefer to combine three procedures, In some cases the doctor will present three alternatives but it will leave the final decision to the patient. This is because the patient needs to know basically three alternatives then to take the decision. There are different therapeutic options for every case of diagnosed mesotelioma. Refill the questionnaire that next appears and from síntomasmesotiloma.com we will send to him specific information about the diagnosis, the prognosis and the clinical judgments.

Additionally there are other therapeutic options at the disposal of the patients. The experimental treatments are attracting more and more attention of the medical field and its results are so encouraging that it does that it should know always to know.

These experimental treatments include the photodynamic therapy, the genetic therapy, the immunotherapy, the therapy with ozone and the hormonal therapy. Also many of the alternative therapies are successful between the patients because they treat the symptoms, although it is an important knowledge that they do not treat the cancer

He recovers for the mesotelioma


Although there is no priest for the mesotelioma, the patients have many options as regards its cancer. Commonly the patients surrender to treatments that it has finally to fight against the cancer, but there are persons who have the option to surrender to clinical essays. Although the clinical essays are not exempt from risks, the patients have the opportunity to prove new treatments and medicines before they are recommended to the public in general. Many medicines and therapies arise as a result from clinical essays and can suppose real finds both in the treatment of the symptomatology and in the extension of the life expectancy.
The multimodal treatment is different approach that has proved that is instrumental in the struggle against the mesotelioma. A multimodal treatment combines two or more treatments, applying them at the same time or one after other, The doctors with habitualidad recommend this option given the good results that it has given in the past. A multimodal treatment that has been published like example in the medical magazine “Chest”, was reflecting like a 52-year-old patient diagnoticado with a malignant estadío mesotelioma pleural I he surrendered to a neumonectomia extrapleural followed by chemotherapy and by radiation in the pectoral wall. The patient is at present alive and does not demonstrate illness after two years of the illness. The multimodal therapy has demonstrated big successes in the tratameinto of this illness and in the life expectancy of the pacienter.

To know that there is no priest for the mesotelioma can be discouraging and terrifying for the patient and its dears, but the survivors’ histories continuously inspire and give hope to those that fight against the cancer.

intervention of the mesotelioma


As regards the mesotelioma there are three types of intervention: diagnostic, curative and palliative. Some of the surgeries can have for an object more of one of the categories earlier stated. For example the toracotomía is a procedure that is used to confirm the diagnosis but that also is used to improve the symptoms of the illness and to clean carcinogenic areas. It is an important knowledge that with of all the interventions, only the curative ones can re-cut the carcinogenic tumors of the patient.

Some of the surgical alteIrnatives are, the braquiterapia, the neumonectomía, the neumonectomía extrapleural, the Toracoscopia and the toracotomía. Although many surgical alternatives exist, the best defense in the struggle against the cancer is to take the mesotelioma in its earliest estadíos when the surgery is still a viable option. Unfortunately due to the latency period, the mesotelioma normally is not detected until the cancer has advanced to estadíos more advanced where the surgery is already not an option.

Radiation for mesotelioma


The radiation therapy uses beams which target the carcinogenic cells are and to destroy them in a finished way. The radiation does not imply internal exhibition of any type. Nevertheless, the radiation “goes off” out of the body across beams. These beams are focused straight in the carcinogenic cells and it can have a positive effect in the reversion of the cancer. The radiation is very popular like way of treating the put mesotelioma that can brake the growth of the carcinogenic cells. The process is not very different to do a radiography to him with x-rays. Obviously to use this skill implies more meetings that go beyond a simple photo. The time of duration of the treatment also is much longer.

A specific form of radiation is the braquiterapia. This procedure implies exhibiting the previous abdomen and the pectoral cavity to radiation to kill to the carcinogenic cells. This procedure is used commonly when the patient from a physical point of view cannot surrender to a surgery.
Chemotherapy
The chemotherapy is considered to be the best well-known way of treating the cancer. It implies using medicines for oral route or injectable such like the Alimta or the Cisplatin that brakes quickly the growth of the carcinogenic cells. With the mesotelioma, the medicines are injected straight into the pectoral cavity or into the abdominal region. If the chemotherapy is or not the best footpath to be continued, it is going to depend on the state in which the cancer is. In some cases the chemotherapy can be the primary treatment while in other cases it is used like supplement to other treatments.

There has been discovered a new form of chemotherapy called Heated Intraperitioneal Chemotherapy (HIPEC) and can be promising for those persons diagnosed with a mesotelioma peritoneal. This treatment, which is carried out of a surgery, uses an enema intrabdominal done with agents quimioterápicos that warm up to a very high temperature. The target is to eliminate the metástasis that for being too small cannot be eliminated by surgery.

Physical therapy


All the standardized forms of treatments for the cancer (chemotherapy, radiation and surgeries) need a physical therapy or rehabilitation. And it because it is necessary to be strong to confront the strong impact of the treatment.

Photodynamic therapy


The photodynamic therapy uses the energy of the light to eradicate the carcinogenic cells leaving the healthy cells without touching. During the treatment, the medicines fotosensibilizadores administer the patients to do to the cells extremely sensitive to the light. The cells that have talked each other with the medicines are submitted to longitudinal light waves, shooting them to create a poisonous form of oxygen that turns in destructive for any carcinogenic cell into the treated area.
Physical therapy
All the standardized forms of treatments for the cancer (chemotherapy, radiation and surgeries) need a physical therapy or rehabilitation. And it because it is necessary to be strong to confront the strong impact of the treatment.

Photodynamic therapy
The photodynamic therapy uses the energy of the light to eradicate the carcinogenic cells leaving the healthy cells without touching. During the treatment, the medicines fotosensibilizadores administer the patients to do to the cells extremely sensitive to the light. The cells that have talked each other with the medicines are submitted to longitudinal light waves, shooting them to create a poisonous form of oxygen that turns in destructive for any carcinogenic cell into the treated area. A few days after the injection of the medication, the patient is exposed to a light with a few predetermined waves. If the carcinogenic cells absorb the light, they begin producing the poisonous oxygen that ends up by eliminating the cells. This therapy also damages to the blood glasses of inside the tumor doing to them that they could not absorb nutrients.

Gene therapy


When not infectious virus is altered genetically it produces a protein which target the carcinogenic cells are making them more vulnerable. This process is named a gene therapy. When the carcinogenic cells are extravulnerable due to the therapy, they turn in capable to the medicines used in the chemotherapy. This popular form of treatment forces to the carcinogenic cells to produce a substance that causes its own death. This procedure produces encouraging results and at the moment one finds in clinical essay alternative Therapies
The alternative therapies are any other not traditional therapy used like complement to the treatments standard of such mesotelioma like chemotherapy and radiation. These natural alternatives use vitamins, grasses, aminos acidic and other natural supplements that are not poisonous. Put these alternative treatments are used more to relieve the symptoms and are not curative measurements, normally there are named complementary treatments.

Other alternative forms include the yoga, the reiki, the cupping and the massages therapy. The studies demonstrate that more than 70 per cent of the patients of cancer complement the traditional treatments with alternative therapies to reduce the effects of the cancer and its symptoms. Also these methods can be like palliative measurements when the traditional treatments are not an option since the patient is in the last estadíos of the mesotelioma

INTRODUCTION


The diffuse mesotelioma is a slightly frequent malignant neoplasia that comes from the cells mesoteliales, being the pleura its most habitual location, they thinking that 10 % of the cases is located at level peritoneal1.

The mesotelioma is usually diagnosed in the fifth decade of the life with a clear predominance in the masculine, due sex the above mentioned to its relation with the labor exhibition to the asbestos. Its incidence is increasing in Europe, they waiting for a peak of the same one in the year 2018, affecting to the cohort of born males between 1945 and 19502, although, the incidence changes of considerable form in different geographical areas, reflecting the possibility of environmental and occupational exhibition to the asbestos. To emphasize also that the incidence increases in a linear way as regards the intensity of the exhibition, but in an exponential way with regard to the time passed from the first exhibition.

ETIOLOGY AND PATOGENIA
The exhibition to the asbestos is the main risk factor for the development of the mesotelioma. The first association between asbestos and cancer was established in 1955 in a study cases – control3, appearing in 1960 information that were relating it also to the mesotelioma pleural4. Since it has been exhibited in previous chapters, there exist two types of fibers of asbestos, the “curvilinear” (crisolita) and the “rectilinear” (crocidolita), being the above mentioned the principally involved ones in the tumor patogenia on having been transported towards the periphery of the lung and to contact the surface pleural, while the first ones remain in the central airlines and are eliminated by major facility. The latency period between the initial exhibition and the death changes extensively, being the average of 48 años5.

Numerous epidemiologic studies have demonstrated the relation between the exhibition to asbestos and the mesotelioma, as well as the development of the same one after the intrapleural instillation or inhalation of fibers of asbestos. Nevertheless, although 80 % of the patients has exhibition history to asbestos, only 10 % of the exposed ones develops mesotelioma6,7 what suggests the existence of other associate factors between which one emphasizes the role granted to the simian virus SV-40 as cofactor in the patogénesis of the mesotelioma after the expression of viral sequence is verified in models animales8. Some chromosomal abnormalities since delecciones of the regions 1q, 3p, 9p and 6q of the chromosome 22 have been quoted also in the patogenia of the mesotelioma.

Antman and col9 and Roviaro and col10 they have found relation between the existence of previous radiation and presence of calcification postuberculosa, respectively, with cases of mesotelioma. There is no definitive evidence of which the tobacco increases the risk of developing the illness.

CLINICAL DECLARATIONS
Approximately two thirds of the patients who are diagnosed are in the status of age understood between the 40 and 70 years. In diverse series11,12, l